Family: Coronaviridae
ACE2
| Species Image | Species | Top 5 cell types expressing ACE2 (Human coronavirus NL63) | Detail |
|---|---|---|---|
|
Marmoset
Tested tissue: Embryo / TotalBrain |
Embryo-animal zygote : 100.00% Embryo-blastoderm cell : 73.68% Embryo-morula cell : 49.06% Embryo-inner cell mass native cell : 48.76% TotalBrain-Immune cells : 0.00% |
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Human
Tested tissue: Liver / Lung / Placenta / Decidua / Blood / Spleen / PBMC / BrainCortex / Adult AdrenalGland / Adult Artery / Adult AscendingColon / Adult Bladder / Adult BoneMarrow / Adult Cerebellum / Adult Cervix / Adult Colon / Adult Duodenum / Adult Epityphlon / Adult Esophagus / Adult Fallopiantube / Adult Gallbladder / Adult Heart / Adult Ileum / Adult Jejunum / Adult Kidney / Adult Liver / Adult Lung / Adult Muscle / Adult Omentum / Adult Pancreas / Adult PeripheralBlood / Adult Pleura / Adult Prostate / Adult Rectum / Adult SigmoidColon / Adult Spleen / Adult Stomach / Adult TemporalLobe / Adult Thyroid / Adult Trachea / Adult TransverseColon / Adult Ureter / Adult Uterus / ChorionicVillus / CordBlood / CordBloodCD34P1 / CordBloodCD34P2 / Fetal AdrenalGland / Fetal Brain / Fetal Calvaria / Fetal Eyes / Fetal FemaleGonad / Fetal Heart / Fetal Intestine / Fetal Kidney / Fetal Liver / Fetal Lung / Fetal MaleGonad / Fetal Muscle / Fetal Pancreas / Fetal Rib / Fetal Skin / Fetal SpinalCord / Fetal Stomach / Fetal Thymus / hESC / NeonatalAdrenalGland / AnteriorCingulateCortex / PrefrontalCortex / Teeth / Testis / FoveaRetina / Endometrium / Cornea / PeripheralRetina |
Placenta-dS2 : 100.00% Placenta-NK CD16+ : 50.00% Fetal AdrenalGland-Hepatocyte-like cell : 45.68% Fetal Intestine-Enterocyte_APOA2 high : 39.16% Adult Jejunum-Enterocyte_APOA1 high : 34.24% |
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Caenorhabditis elegans
Tested tissue: Embryo |
Embryo-ABpr : 80.00% Embryo-P0 : 80.00% Embryo-Ea : 75.00% Embryo-ABp : 60.00% Embryo-ABA : 60.00% |
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|
Cat
Tested tissue: Esophagus / Eyelid / Heart / Kidney / Liver / Lung / Rectum / PBMC |
Kidney-Proximal tubule cells : 71.54% Heart-Epicardial cells : 57.14% Kidney-Stromal cells : 44.00% Eyelid-Endothelial cells : 34.55% Rectum-Enteroendocrine cells : 25.68% |
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|
Mouse
Tested tissue: PBMC / Lung / TotalBrain / Bladder / BoneMarrow / BoneMarrowcKit / Brain / EmbryonicMesenchymeE14.5 / Fetal Brain / Fetal FemaleGonad / Fetal Intestine / Fetal Lung / Fetal MaleGonad / Fetal Stomach / Kidney / Liver / MammaryGland.Involution / MammaryGland.Lactation / MammaryGland.Pregnancy / MammaryGland.Virgin / MesenchymalStemCells / MesenchymalStemCellsPrimary / Muscle / NeonatalCalvaria / NeonatalHeart / NeonatalMuscle / NeonatalPancreas / NeonatalRib / NeonatalSkin / Ovary / Pancreas / PeripheralBlood / PlacentaE14.1 / PlacentaE14.2 / Prostate / SmallIntestine / Spleen / Stomach / Testis / TrophoblastStemCells / Uterus / Teeth / Adipose / PrimaryVisualCortex / CardiacVentricle |
SmallIntestine-Epithelium of small intestinal villi_Fabp6 high : 68.90% SmallIntestine-Epithelium of small intestinal villi_Fabp6 high : 62.79% SmallIntestine-Epithelium of small intestinal villi_Fabp1 high : 47.54% SmallIntestine-Epithelium of small intestinal villi_Fabp1 high : 44.83% Pancreas-Smooth muscle cell_Rgs5 high : 41.67% |
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|
Rat
Tested tissue: Lung / UrogenitalSinus / TotalBrain |
Lung-Secretory : 61.80% Lung-Secretory : 48.51% Lung-Ciliated : 34.62% UrogenitalSinus-smooth muscle, peri-urethral mesenchyme and urethral epithelium : 31.82% Lung-ATII : 28.78% |
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Alpaca
Tested tissue: Frontal / Liver / Lung / PBMC |
Liver-Hepatocytes : 31.07% Liver-Immune cells : 9.20% Frontal-Endothelial cells : 6.67% Liver-Hepatic stellate cells : 6.50% Liver-Liver sinusoidal endothelial cells : 5.24% |
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|
Mink
Tested tissue: Frontal / Kidney / Liver / Lung |
Kidney-Distal convoluted tubule cells : 29.16% Kidney-Proximal tubule cells : 16.56% Kidney-Urothelium cells : 9.80% Kidney-Collecting duct principal cells : 7.08% Kidney-Collecting duct transient cells : 5.80% |
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Hamster
Tested tissue: Frontal / Heart / Kidney / Liver / Lung / PBMC / TotalBrain |
Heart-Cardiomyocytes : 23.50% Kidney-Endothelial cells : 7.78% Lung-Ciliated cells : 5.79% Lung-Mesothelial cells : 5.75% Kidney-Mesangial cells : 5.68% |
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Pig
Tested tissue: Lung / Frontal / Occipital / Parietal / Hypothalamus / Temporal |
Lung-B_Jchain+ : 23.36% Lung-Cell_cycle : 17.58% Lung-DC : 15.25% Lung-Mac_alv : 13.87% Lung-Ciliated : 12.90% |
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Pangolin
Tested tissue: Duodenum / Esophagus / Heart / Kidney / LargeIntestine / Liver / Lung / Spleen / Stomach |
Spleen-Dendritic cells : 17.72% Heart-Pericytes : 6.46% Kidney-Proximal tubule cells : 5.78% Kidney-Collecting duct cells : 2.93% Kidney-Podocytes : 2.75% |
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Tiger
Tested tissue: Heart / Kidney / Liver / Lung / Spleen / PBMC |
Liver-Cholangiocytes : 12.82% Kidney-Proximal tubule cells : 5.88% Liver-Hepatocytes : 5.75% Kidney-Podocytes : 5.26% Lung-Secretory cells : 5.09% |
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Civet
Tested tissue: Frontal / Kidney / Liver / Lung / Spleen |
Kidney-Proximal tubule cells : 10.66% Kidney-Collecting duct intercalated cells : 5.33% Kidney-Endothelial cells : 5.26% Kidney-Collecting duct principal cells : 3.97% Kidney-Distal convoluted tubule cells : 3.48% |
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Zebrafish
Tested tissue: KidneyMarrow / Gut / PBMC / TotalBrain |
KidneyMarrow-mature T cell : 6.45% Gut-blood cell : 6.35% KidneyMarrow-thymic T cell : 2.63% KidneyMarrow-hematopoietic stem cell and thrombocyte : 0.00% KidneyMarrow-hematopoietic stem cell : 0.00% |
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Crab-eating macaque
Tested tissue: AorticArtery / CoronaryArtery / TotalBrain |
AorticArtery-Aortic artery_endothelial cell : 5.18% AorticArtery-Coronary artery_endothelial cell1 : 5.15% CoronaryArtery -Aortic artery_endothelial cell : 4.08% AorticArtery-Adventitial fibroblast : 2.23% AorticArtery-Immune cell : 2.05% |
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Hedgehog
Tested tissue: Brain / Kidney |
Kidney-Urothelium cells : 3.92% Kidney-Proximal tubule cells : 3.03% Kidney-PER : 2.42% Kidney-Cell cycling : 1.92% Brain-Smooth muscle cells : 1.72% |
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Chicken
Tested tissue: PrimitiveStreak / AnteriorNeuralTube / TotalBrain |
PrimitiveStreak-embryonic cell : 3.43% AnteriorNeuralTube-neural crest cell : 1.40% TotalBrain-Immune cells : 0.00% |
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Lizard
Tested tissue: Lung / Pallium |
Lung-Ciliated cells : 3.18% Pallium-pvInh2 : 1.18% Pallium-pvInh1 : 0.64% Lung-Fibroblasts : 0.53% Lung-ATII : 0.53% |
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Goat
Tested tissue: Lung / PBMC |
Lung-Ciliated cells : 3.12% Lung-Endothelial cells : 0.89% Lung-ATI : 0.31% Lung-Smooth muscle cells : 0.23% PBMC-B cells : 0.19% |
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Rabbit
Tested tissue: Lung / PBMC |
Lung-Fibroblasts : 1.92% Lung-Macrophages : 0.00% Lung-T cells : 0.00% Lung-ATII : 0.00% Lung-Endothelial cells : 0.00% |
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Blind mole rat
Tested tissue: TotalBrain |
TotalBrain-Microglia : 1.56% |
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Bat
Tested tissue: Lung |
Lung-Ciliated cells : 1.29% Lung-Secretory cells : 0.57% Lung-ATI : 0.20% Lung-ATII : 0.19% Lung-Fibroblasts : 0.17% |
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Chinchilla
Tested tissue: Brain / Kidney |
Kidney-B cells : 1.05% Kidney-Collecting duct transient cells : 0.81% Kidney-Proximal tubule cells : 0.63% Brain-Smooth muscle cells : 0.38% Kidney-Collecting duct intercalated cells : 0.31% |
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|
Dog
Tested tissue: Lung / PBMC |
PBMC-UN : 0.85% PBMC-B cells : 0.68% Lung-Ciliated cells : 0.23% Lung-ATII : 0.23% Lung-ATI : 0.20% |
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Rhesus monkey
Tested tissue: DorsolateralPrefrontalCortex |
DorsolateralPrefrontalCortex-ExN7 : 0.78% DorsolateralPrefrontalCortex-OPC : 0.66% DorsolateralPrefrontalCortex-Peri : 0.54% DorsolateralPrefrontalCortex-ExN1 : 0.51% DorsolateralPrefrontalCortex-InN2 : 0.39% |
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Pig-tailed macaque
Tested tissue: LateralGeniculateNucleus |
LateralGeniculateNucleus-LGN Exc IL15RA : 0.53% LateralGeniculateNucleus-LGN Exc PRKCG KCNH3 : 0.00% LateralGeniculateNucleus-No Class : 0.00% LateralGeniculateNucleus-LGN Inh DFNB31 : 0.00% LateralGeniculateNucleus-LGN Inh DSEL : 0.00% |
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Turtle
Tested tissue: Pallium |
Pallium-tsExc1 : 0.42% Pallium-tsExc3 : 0.19% Pallium-tsExc5 : 0.18% Pallium-tsExc4 : 0.04% Pallium-tsOPC : 0.00% |
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Deer
Tested tissue: Lung / PBMC |
Lung-Fibroblasts : 0.40% Lung-ATI : 0.20% Lung-Endothelial cells : 0.12% Lung-ATII : 0.10% Lung-B cells : 0.04% |
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Pigeon
Tested tissue: Lung / PBMC |
Lung-Fibroblasts : 0.27% Lung-ATI : 0.00% Lung-Macrophages : 0.00% Lung-Ciliated cells : 0.00% Lung-Endothelial cells : 0.00% |
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Peacock
Tested tissue: PBMC |
PBMC-Red blood cell : 0.04% PBMC-Neutrophil : 0.00% PBMC-B cells : 0.00% PBMC-Platelets : 0.00% PBMC-NK : 0.00% |
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Sheep
Tested tissue: BrainCortex |
BrainCortex-Microglia : 0.00% |
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